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低剂量甲氨蝶呤作为皮肌炎并发睑外翻手术的辅助治疗方法。

Low-dose methotrexate as an adjunctive therapy with surgery for ectropion complicating dermatomyositis.

作者信息

Abernethy M L, Arterberry J F, Callen J P

机构信息

Department of Medicine, University of Louisville, Ky., USA.

出版信息

Dermatology. 1996;192(2):153-5. doi: 10.1159/000246346.

Abstract

We describe the clinical and histopathologic features of a 44-year-old woman who developed bilateral lower eyelid ectropion and upper lid entropion presumably secondary to dermatomyositis. A variety of inflammatory, infiltrative and/or scarring dermatoses have been associated with ectropion. Chronic inflammation, poikilodermatous change and mucinous infiltration of the eyelids due to dermatomyositis are the postulated mechanisms leading to ectropion in our patient. This case is unique in that neither dermatomyositis nor papular mucinosis has previously been reported as a cause of ectropion. Also interesting was the adjunctive effect of methotrexate therapy.

摘要

我们描述了一名44岁女性的临床和组织病理学特征,她出现双侧下睑外翻和上睑内翻,推测继发于皮肌炎。多种炎症性、浸润性和/或瘢痕性皮肤病与睑外翻有关。皮肌炎导致的慢性炎症、皮肤异色症改变和眼睑黏液浸润是我们患者发生睑外翻的假定机制。该病例的独特之处在于,此前从未有皮肌炎或丘疹性黏蛋白病作为睑外翻病因的报道。甲氨蝶呤治疗的辅助作用也很有趣。

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