Casanova Bellido M, Moreno Vázquez A M, Ferriz Mas B, Casanova Román M, Rico de Cos S, Tapia Barrios J M
Hospital Universitario de Puerto Real, Cádiz.
An Esp Pediatr. 1996 Feb;44(2):145-8.
The objective of this study has been to know the copper levels in maternal and cord blood at delivery, the relationships between them, and the influence that maternal age, parity, social class, sex, gestational age and anthropometric parameters have over them.
Copper levels in serum from one hundred mothers and their newborns have been determined by atomic absorption spectrophotometry.
The mean copper level in maternal serum was 232.4 +/- 31.3 micrograms/100 ml, and 50.2 +/- 18.4 micrograms/100 ml in cord blood. We do not find any influence of maternal age, parity, sex and neonatal anthropometry over these levels. We see an ascending tendency of serum copper in the newborns as they increase their gestational age, and in mothers as soon as they belong to a lower socioeconomic level. There is a significant difference between the cord copper levels of newborns from mothers with serum copper levels less or equal to P25 or P50 and those from ones over P75, and a significant positive correlation between maternal and newborns ones.
Our results show the relationship between the maternal and neonatal copper status, the influence of the socioeconomic situation on the maternal levels, and the age gestational age on the newborns ones.
本研究的目的是了解分娩时母血和脐血中的铜水平、它们之间的关系,以及母亲年龄、产次、社会阶层、性别、孕周和人体测量参数对其的影响。
采用原子吸收分光光度法测定了100名母亲及其新生儿血清中的铜水平。
母血血清铜平均水平为232.4±31.3微克/100毫升,脐血为50.2±18.4微克/100毫升。我们未发现母亲年龄、产次、性别和新生儿人体测量学对这些水平有任何影响。我们发现,随着孕周增加,新生儿血清铜呈上升趋势;母亲社会经济水平越低,其血清铜水平越高。血清铜水平低于或等于第25百分位数(P25)或第50百分位数(P50)的母亲所生新生儿的脐血铜水平与血清铜水平高于第75百分位数(P75)的母亲所生新生儿的脐血铜水平之间存在显著差异,且母血与新生儿血铜水平之间存在显著正相关。
我们的结果显示了母血和新生儿血铜状态之间的关系、社会经济状况对母血铜水平的影响,以及孕周对新生儿血铜水平的影响。