O'Connell J E, Gray C S
South Tyneside District Hospital, Tyne and Wear.
Age Ageing. 1996 Jul;25(4):307-9. doi: 10.1093/ageing/25.4.307.
Atrial fibrillation (AF) is an important and independent risk factor for stroke, particularly in elderly people. The efficacy of treatment with warfarin and aspirin in primary and secondary stroke prevention in AF has been demonstrated in randomized clinical trials. In a demographic study, we examined the prevalence of AF in patients registered with a general practice in the North East of England; 91 patients with known AF were identified, 69 with chronic AF and 22 with paroxysmal AF. The mean duration of the arrhythmia was 6.43 years and the prevalence of AF increased with age. There was a high prevalence of cerebrovascular disease in AF patients. The majority of AF patients were not receiving therapy with aspirin or warfarin as primary or secondary stroke prevention. If strategies for stroke prevention in AF are to be applied to the community, general practitioners will need to play a more active part.
心房颤动(AF)是中风的一个重要且独立的危险因素,在老年人中尤为如此。华法林和阿司匹林用于房颤一级和二级预防的疗效已在随机临床试验中得到证实。在一项人口统计学研究中,我们调查了在英格兰东北部一家普通诊所登记的患者中房颤的患病率;共识别出91例已知房颤患者,其中69例为慢性房颤,22例为阵发性房颤。心律失常的平均持续时间为6.43年,房颤患病率随年龄增长而增加。房颤患者中脑血管疾病的患病率很高。大多数房颤患者未接受阿司匹林或华法林作为一级或二级预防中风的治疗。如果要将房颤中风预防策略应用于社区,全科医生将需要发挥更积极的作用。