Hicks V A, Chen S C, Kritchevsky D
Kellogg Company, Science and Technology Center, Battle Creek, MI 49016-2432 USA.
Artery. 1995;21(6):352-61.
Hamsters were fed high fiber diets containing cellulose, wheat bran or psyllium. The psyllium was incorporated into high fiber, ready-to-eat (RTE) flakes that were used to formulate the test diet. All the diets contained 0.125% cholesterol. The study was terminated after three weeks. Food intake, weight gain and feed efficiency were not significantly different in the three groups. Serum total and HDL cholesterol levels were reduced significantly by the psyllium diet. Serum triglycerides were 26% lower in the hamsters fed psyllium but because of the large variation the difference did not reach statistical significance. Liver total cholesterol and cholesteryl ester levels were significantly lower in the hamsters fed psyllium. Liver triglycerides were highest in the psyllium-fed hamsters and liver phospholipid levels were similar in the three groups. Liver cholesterol and triglyceride levels were higher in hamsters fed cellulose than in those fed wheat bran. Psyllium formulated into an RTE cereal was effective in reducing serum and liver cholesterol levels in hamsters.
给仓鼠喂食含有纤维素、麦麸或车前子壳的高纤维饮食。将车前子壳加入高纤维即食（RTE）薄片中，用于配制试验饮食。所有饮食都含有0.125%的胆固醇。三周后该研究结束。三组的食物摄入量、体重增加和饲料效率没有显著差异。车前子壳饮食显著降低了血清总胆固醇和高密度脂蛋白胆固醇水平。喂食车前子壳的仓鼠血清甘油三酯降低了26%，但由于差异变化较大，未达到统计学显著性。喂食车前子壳的仓鼠肝脏总胆固醇和胆固醇酯水平显著较低。喂食车前子壳的仓鼠肝脏甘油三酯最高，三组的肝脏磷脂水平相似。喂食纤维素的仓鼠肝脏胆固醇和甘油三酯水平高于喂食麦麸的仓鼠。制成即食谷物的车前子壳能有效降低仓鼠的血清和肝脏胆固醇水平。
