克拉霉素治疗早期莱姆病：一项试点研究。
Clarithromycin in treatment of early Lyme disease: a pilot study.
作者信息
Dattwyler R J, Grunwaldt E, Luft B J
机构信息
Lyme Disease Center, State University of New York at Stony Brook 11794-8161, USA.
出版信息
Antimicrob Agents Chemother. 1996 Feb;40(2):468-9. doi: 10.1128/AAC.40.2.468.
Abstract
Forty-one patients with erythema migrans were enrolled in an open-labelled pilot study of oral clarithromycin, 500 mg twice daily for 21 days, for the treatment of early Lyme disease. Immediately posttherapy, pretreatment signs and symptoms resolved among 91% of the 33 evaluable patients. At 6 months, all 28 of the evaluable patients were well. Clarithromycin shows promise as an effective agent for the treatment of early Lyme disease and warrants further study.
摘要
41例皮肤游走性红斑患者参与了一项口服克拉霉素的开放性初步研究，剂量为每日2次，每次500mg，疗程21天，用于治疗早期莱姆病。治疗后即刻，33例可评估患者中有91%的患者治疗前的体征和症状消失。6个月时，所有28例可评估患者情况良好。克拉霉素有望成为治疗早期莱姆病的有效药物，值得进一步研究。
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