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幽门螺杆菌对消化治疗剂中西甲硅油乳化剂的独特敏感性。

Unique susceptibility of Helicobacter pylori to simethicone emulsifiers in alimentary therapeutic agents.

作者信息

Kane A V, Plaut A G

机构信息

Gastroenterology Division, New England Medical Center Hospital, Boston, Massachusetts 02111, USA.

出版信息

Antimicrob Agents Chemother. 1996 Feb;40(2):500-2. doi: 10.1128/AAC.40.2.500.

Abstract

Helicobacter pylori is killed in vitro by polyoxyethylene acyl esters and ethers similar to simethicone emulsifiers in therapeutic antifoams. The MBC of these compounds for Helicobacter pylori was less than 20 micrograms/ml, while other gram-negative bacteria were unaffected by much higher concentrations of up to 50 mg/ml.

摘要

幽门螺杆菌在体外可被类似于治疗性消泡剂中西甲硅油乳化剂的聚氧乙烯酰酯和醚类杀死。这些化合物对幽门螺杆菌的最低杀菌浓度小于20微克/毫升,而其他革兰氏阴性菌在高达50毫克/毫升的更高浓度下不受影响。

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本文引用的文献

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N Engl J Med. 1991 Oct 17;325(16):1127-31. doi: 10.1056/NEJM199110173251603.

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