Sensi A, Gruppioni R, Bonfatti A, Rubini M, Giunta C, Fontana F
Institute of Medical Genetics, USL 31 Ferrara, Italy.
Eur J Histochem. 1995;39(4):317-20.
The recent techniques of chromosome painting allow the molecular comparison of chromosomes from distantly related mammals. Here we show a modified ZOO-FISH technique based on lower stringency which allows to identify syntenic regions between human and Indian muntjac chromosomes. While when probing with human chromosome 2, no consistent cluster of hybridization were observed, with human chromosome 9, a number of discrete fluorescent regions along the Indian muntjac chromosomes were found.
最近的染色体涂染技术能够对远缘哺乳动物的染色体进行分子比较。在此我们展示了一种基于较低严谨度的改良荧光原位杂交技术（ZOO-FISH），该技术可用于识别人类和印度麂染色体之间的同线区域。在用人类2号染色体进行探测时，未观察到一致的杂交簇；而在用人类9号染色体探测时，在印度麂染色体上发现了一些离散的荧光区域。
