Infection of a total knee arthroplasty by Candida parapsilosis. A case report of successful treatment by joint reimplantation with a literature review.

This article describes a case of total knee infection by Candida parapsilosis treated by joint reimplantation. Surgical treatment consisted of resection arthroplasty with wound stablization by external fixation. Antibiotic treatment consisted of 6 weeks of intravenous amphotericin B and 7 weeks of oral 5-fluorocytosine begun at the time of resection arthroplasty. Cultures at reimplantation were negative. Reimplanted components were all cemented with perioperative cefazolin antibiotic. No further antifungal treatment was necessary.