Saleh A Z, Yamanaka K, Niki H, Ogura T, Yamazoe M, Hiraga S
Department of Molecular Cell Biology, Kumamoto University School of Medicine, Japan.
FEMS Microbiol Lett. 1996 Oct 1;143(2-3):211-6. doi: 10.1111/j.1574-6968.1996.tb08482.x.
The purified MukB protein of Escherichia coli has DNA binding activity and nucleotide binding activity. We have isolated a mutation, mukB1013, causing a substitution of valine at position 1379 to leucine. This mutant MukB protein was defective for DNA binding, while the ATP binding activity remained unaffected. A truncated MukB protein that is short of 109 amino acids from the C-terminus failed to bind DNA.
