Gottesman I I, Bertelsen A
Am J Med Genet. 1996 Jul 26;67(4):317-22. doi: 10.1002/(SICI)1096-8628(19960726)67:4<317::AID-AJMG1>3.0.CO;2-J.
The history of psychiatric genetics is informed by this paper, which serves to review the legacy of German psychiatric genetics and its antecedents during the twentieth century. It also serves as an introduction to two new annotated abstracts of basic research papers on family studies of schizophrenia by Ernst Rüdin in 1916 and by Bruno Schulz in 1932, submitted by Kenneth Kendler and Edith Zerbin-Rüdin, together with another paper by them describing the origin and activities of Rüdin's Munich School of Psychiatric Genetics (1917-1945). Our paper also introduces an invited critical summary of the work of Ernst Rüdin by his biographer Matthias M. Weber, a medical historian working in the Historical Archives of the Clinical Institute of the Max Planck Institute of Psychiatry in Munich. We raise a number of bioethical questions in the context of the uses and misuses made of genetic information in the service of the Nazi programs of eugenics, "euthanasia," and genocide.
本文讲述了精神科遗传学的历史，旨在回顾德国精神科遗传学在20世纪的遗产及其前身。它还作为两篇新的带注释的基础研究论文摘要的引言，这两篇论文分别是1916年恩斯特·吕丁（Ernst Rüdin）和1932年布鲁诺·舒尔茨（Bruno Schulz）关于精神分裂症家族研究的论文，由肯尼斯·肯德勒（Kenneth Kendler）和伊迪丝·策宾-吕丁（Edith Zerbin-Rüdin）提交，同时还有他们另一篇描述吕丁慕尼黑精神科遗传学派（1917 - 1945）的起源和活动的论文。我们的论文还引入了由恩斯特·吕丁的传记作者马蒂亚斯·M·韦伯（Matthias M. Weber）撰写的特邀评论摘要，马蒂亚斯·M·韦伯是一位在慕尼黑马克斯·普朗克精神病学临床研究所历史档案馆工作的医学历史学家。我们在将遗传信息用于纳粹优生学、“安乐死”和种族灭绝计划以及滥用遗传信息的背景下，提出了一些生物伦理问题。
