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长期失重对飞行后血浆甲状腺激素的影响。

Prolonged weightlessness effect on postflight plasma thyroid hormones.

作者信息

Leach C S, Johnson P C, Driscoll T B

出版信息

Aviat Space Environ Med. 1977 Jul;48(7):595-7.

PMID:883928
Abstract

Blood drawn before and after spaceflight from the nine Skylab astronauts showed a statistically significant increase in mean plasma thyroxine (T-4) of 1.4 microgram/dl and in thyroid-stimulating hormone (TSH) of 4 muU/ml. Concurrent triiodothyronine (T-3) levels decreased 27 ng/dl indicating inhibited conversion of T-4 to T-3. The T-3 decrease is postulated to be a result of the increased cortisol levels noted during and following each mission. These results confirm the thyroidal changes noted after the shorter Apollo flights and show that thyroid hormone levels change during spaceflight.

摘要

从九名天空实验室宇航员飞行前后采集的血液样本显示,血浆甲状腺素(T-4)平均水平显著增加1.4微克/分升,促甲状腺激素(TSH)增加4微国际单位/毫升。同时,三碘甲状腺原氨酸(T-3)水平下降27纳克/分升,表明T-4向T-3的转化受到抑制。T-3的下降被认为是每次任务期间及之后观察到的皮质醇水平升高所致。这些结果证实了在较短的阿波罗飞行后所观察到的甲状腺变化,并表明甲状腺激素水平在太空飞行期间会发生变化。

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Prolonged weightlessness effect on postflight plasma thyroid hormones.长期失重对飞行后血浆甲状腺激素的影响。
Aviat Space Environ Med. 1977 Jul;48(7):595-7.
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