Strollo Felice, Gentile Sandro, Strollo Giovanna, Mambro Andrea, Vernikos Joan
Diabetes Unit, San Raffaele Institute, Rome, Italy.
Campania University "Luigi Vanvitelli" and Nefrocenter Research Network, Naples, Italy.
Front Physiol. 2018 Nov 12;9:1551. doi: 10.3389/fphys.2018.01551. eCollection 2018.
Astronauts coming back from long-term space missions present with different health problems potentially affecting mission performance, involving all functional systems and organs and closely resembling those found in the elderly. This review points out the most recent advances in the literature in areas of expertise in which specific research groups were particularly creative, and as they relate to aging and to possible benefits on Earth for disabled people. The update of new findings and approaches in space research refers especially to neuro-immuno-endocrine-metabolic interactions, optic nerve edema, motion sickness and muscle-tendon-bone interplay and aims at providing the curious - and even possibly naïve young researchers - with a source of inspiration and of creative ideas for translational research.
从长期太空任务返回的宇航员会出现各种不同的健康问题,这些问题可能影响任务执行,涉及所有功能系统和器官,且与老年人的健康问题极为相似。本综述指出了特定研究小组在专业领域取得的最新进展,这些进展与衰老以及对地球上残疾人可能带来的益处相关。太空研究中新发现和新方法的更新尤其涉及神经 - 免疫 - 内分泌 - 代谢相互作用、视神经水肿、晕动病以及肌肉 - 肌腱 - 骨相互作用,旨在为好奇的——甚至可能是天真的年轻研究人员——提供转化研究的灵感和创意来源。