Eeley E A, Stratton I M, Hadden D R, Turner R C, Holman R R
Diabetes Research Laboratories, Radcliffe Infirnary, Oxford, UK.
Diabet Med. 1996 Jul;13(7):656-62. doi: 10.1002/(SICI)1096-9136(199607)13:7<656::AID-DIA131>3.0.CO;2-5.
Self-reported dietary intake was estimated from 3-day prospective food diaries completed by Type 2 diabetic patients in the UK Prospective Diabetes Study. All patients had received individual dietary advice and had been randomly allocated to diet, sulphonylurea or insulin therapy 3 months after diagnosis. A total of 132 patients (120 white Caucasian, 12 Asian) stratified for gender, obesity and allocated therapy with mean age 55 years (SD 8), body mass index 28 kg m-2 (SD 4), and with a diabetes duration of 3 to 6 years were selected at random from 5 of 23 clinical centres. Patients reported a similar proportion of their energy intake as carbohydrate (43%) to the general population and had not increased to the recommended 50-55%. Their protein intake (21%) was higher than the advised 10-15%. Estimated energy intake from fat (37%) was close to that recommended for diabetic patients (30-35%) and was lower than that reported for the UK population (40%). The estimated polyunsaturated/saturated fat intake ratio (0.48) was higher than that reported for the UK population (0.35) compared with the recommended 1.0. Mean fibre intake at 22 g day-1 was less than the recommended 30 g day-1. The 8 male Asian patients took a higher proportion of their dietary intake as fat (46% vs 37%) and lower as protein (14% vs 21%) than the male white Caucasian patients. No significant differences were seen in estimated nutrient constituents between patients allocated to diet, sulphonylurea or insulin therapy as part of the UK Prospective Diabetes Study and followed for mean 4.2 years (SD1.6). This suggests that dietary factors will not confound UK Prospective Diabetes Study treatment related analyses.
自我报告的饮食摄入量是根据英国前瞻性糖尿病研究中2型糖尿病患者填写的3天前瞻性食物日记估算得出的。所有患者均接受了个性化饮食建议，并在诊断后3个月被随机分配至饮食、磺脲类药物或胰岛素治疗组。从23个临床中心中的5个中心随机选取了132名患者（120名白种人、12名亚洲人），这些患者按性别、肥胖程度分层，并根据分配的治疗方法进行分组，平均年龄55岁（标准差8），体重指数28 kg/m²（标准差4），糖尿病病程为3至6年。患者报告的碳水化合物能量摄入量占比（43%）与普通人群相似，未达到推荐的50 - 55%。他们的蛋白质摄入量（21%）高于建议的10 - 15%。脂肪的估计能量摄入量（37%）接近糖尿病患者推荐水平（30 - 35%），低于英国人群报告水平（40%）。估计的多不饱和/饱和脂肪摄入量比值（0.48）高于英国人群报告水平（0.35），而推荐比值为1.0。平均纤维摄入量为22克/天，低于推荐的30克/天。8名亚洲男性患者饮食中脂肪摄入量占比更高（46%对37%），蛋白质摄入量占比更低（14%对21%），高于白种人男性患者。作为英国前瞻性糖尿病研究的一部分，对分配至饮食、磺脲类药物或胰岛素治疗组的患者进行了平均4.2年（标准差1.6）的随访，结果显示估计的营养成分没有显著差异。这表明饮食因素不会混淆英国前瞻性糖尿病研究中与治疗相关的分析。
