Tarimo D S, Killewo J Z, Minjas J N, Msamanga G I
Department of Parasitology/Medical Entomology, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania.
East Afr Med J. 1996 Jun;73(6):397-9.
A six month study was conducted in north-eastern Tanzania to determine the prevalence of pathogenic intestinal parasites among adult patients with enteropathic AIDS. A total of 352 patients were recruited of whom 158 (45%) had chronic diarrhoea. Of the 352 patients, 123 (35%) had intestinal parasites. Of the 123, 77 (62.6%) patients had chronic diarrhoea. The types of parasites detected were Cryptosporidium, Isospora belli, Strongyloides stercoralis, Schistosoma mansoni, Trichuris, trichiura, Ascaris lumbricoides, hookworm and Entamoeba histolytica. The prevalence of intestinal parasites was significantly higher in patients with chronic diarrhoea than in those without (P < 0.05). Cryptosporidium and Isospora belli were only detected in patients with chronic diarrhoea and were thus the most likely cause of the diarrhoea. This study has established that coccidian parasites are the most important gut opportunistic infections in Tanzanian patients with enteropathic AIDS. The fact that a high proportion of patients with chronic diarrhoea (51.3%) had no identifiable parasitic agents, suggests that other infectious agents or alternative mechanisms other than infections are responsible for the diarrhoea.
在坦桑尼亚东北部开展了一项为期六个月的研究，以确定患有肠道型艾滋病的成年患者中致病性肠道寄生虫的流行情况。共招募了352名患者，其中158名（45%）患有慢性腹泻。在这352名患者中，123名（35%）有肠道寄生虫。在这123名患者中，77名（62.6%）患有慢性腹泻。检测到的寄生虫种类有隐孢子虫、贝氏等孢球虫、粪类圆线虫、曼氏血吸虫、鞭虫、蛔虫、钩虫和溶组织内阿米巴。慢性腹泻患者中肠道寄生虫的流行率显著高于无慢性腹泻的患者（P<0.05）。隐孢子虫和贝氏等孢球虫仅在慢性腹泻患者中检测到，因此很可能是腹泻的病因。该研究证实，球虫寄生虫是坦桑尼亚患有肠道型艾滋病患者中最重要的肠道机会性感染。相当比例的慢性腹泻患者（51.3%）未检测到可识别的寄生虫病原体，这表明腹泻是由其他传染原或感染以外的其他机制引起的。
