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Effect of bicarbonate and other buffers on choroid plexus Na+/K+pump.

作者信息

Wright E M

出版信息

Biochim Biophys Acta. 1977 Aug 1;468(3):486-9. doi: 10.1016/0005-2736(77)90297-8.

DOI:10.1016/0005-2736(77)90297-8
PMID:884095
Abstract

The Na+/K+ pump on the apical membrane of the choroid plexus epithelium was found to be sensitive to bicarbonate. Glycodiazine, a non-volatile, lipid soluble buffer with a pK of 5.7, mimicked the effect of bicarbonate, and was transported across the epithelium in the same direction as sodium. These results are explained in terms of a Na+/H+ exchange mechanism on the basal-lateral membrane.

摘要

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