Kuroki S, Saida T, Nukina M, Haruta T, Yoshioka M, Kobayashi Y, Nakanishi H
Department of Pediatrics, Kobe City General Hospital, Japan.
Ann Neurol. 1993 Mar;33(3):243-7. doi: 10.1002/ana.410330304.
Campylobacter jejuni was isolated from stool cultures from 14 (30%) of 46 patients with Guillain-Barré syndrome and from 6 (1.2%) of 503 healthy persons, and the difference was highly significant (p < 0.0001). In addition, serological evidence of recent C. jejuni infection was found in 5 of 29 patients with negative stool cultures. Therefore, 41% of patients were associated with C. jejuni infection. Ten of 12 (83%) isolates from patients with Guillain-Barré syndrome belonged to Penner serogroup 19, which is a rare serogroup in sporadic patients with C. jejuni enteritis. In the lectin typing study, all serogroup 19 strains from patients with Guillain-Barré syndrome were shown to contain terminal beta-N-acetylglucosamine residues on their cell surface, but serogroup 19 strains from patients with enteritis were not.
空肠弯曲菌从46例格林-巴利综合征患者中的14例（30%）粪便培养物中分离得到，从503名健康人中的6例（1.2%）粪便培养物中分离得到，差异具有高度显著性（p < 0.0001）。此外，在29例粪便培养阴性的患者中，有5例发现了近期空肠弯曲菌感染的血清学证据。因此，41%的患者与空肠弯曲菌感染有关。12株来自格林-巴利综合征患者的菌株中有10株（83%）属于彭纳血清群19，这在散发性空肠弯曲菌肠炎患者中是一个罕见的血清群。在凝集素分型研究中，所有来自格林-巴利综合征患者的血清群19菌株在其细胞表面均显示含有末端β-N-乙酰葡糖胺残基，但来自肠炎患者的血清群19菌株则没有。
