Shatemirova K K, Vervkina I V, Gorkin V Z
Biull Eksp Biol Med. 1977 Jun;83(6):669-70.
Chlorgyline, a selective monoamine oxidase (MAO) of the A type inhibitor, contrary to deprenil--MAO of the B type inhibitor, prevented the appearance in the rat liver mitochondrial membrane fragments incubated under aerobic conditions of qualitatively new properties to deaminate histamine or AMP. Apparently the MAO of A type but not of B type underwent a qualitative alteration (transformation) of catalytic properties under conditions favourable for partial oxidation of SH-groups.
A型选择性单胺氧化酶（MAO）抑制剂氯吉兰，与B型MAO抑制剂去甲丙咪嗪相反，在有氧条件下温育的大鼠肝线粒体膜碎片中，可防止对组胺或AMP脱氨基的全新性质的出现。显然，在有利于SH基团部分氧化的条件下，A型而非B型MAO发生了催化性质的质变（转化）。
