Knesevich J W, Biggs J T, Clayton P J, Ziegler V E
Br J Psychiatry. 1977 Jul;131:49-52. doi: 10.1192/bjp.131.1.49.
In 26 depressed patients, a high correlation (0-89) was found between the Hamilton score and a psychiatrist's global rating and between the change (0-68) in these ratings during treatment. The Hamilton scale was able to differentiate at the o-01 level four degrees of severity based on the global rating. Limiting the range of severity measured was found to lower significantly the correlation between the ratings. A prospective examination of a six-item sub-scale of the Hamilton scale developed by Beck and associates failed to confirm its claimed improvement in sensitivity or validity.
在26名抑郁症患者中，发现汉密尔顿评分与精神科医生的整体评定之间存在高度相关性（0.89），且在治疗期间这些评定的变化（0.68）之间也存在高度相关性。汉密尔顿量表能够根据整体评定在0.01水平上区分出四个严重程度等级。研究发现，限制所测量的严重程度范围会显著降低评定之间的相关性。对贝克及其同事编制的汉密尔顿量表的一个六项子量表进行的前瞻性检验未能证实其在敏感性或效度方面所宣称的改善。
