Austin J R, el-Naggar A K, Goepfert H
Department of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, Houston, USA.
Otolaryngol Clin North Am. 1996 Aug;29(4):611-27.
Medullary thyroid carcinoma in both sporadic and familial forms is a curable disease if detected early and treated by the proper surgery. The advent of genetic screening for the RET protooncogene portends great promise in the earlier diagnosis and treatment of familial forms of MTC. New chemotherapy protocols have produced some tumor regression in patients with metastatic MTC. Improved use of Adriamycin and hyper-fractionated radiotherapy combined with debulking procedures has prolonged survival in anaplastic thyroid cancer. Thyroid gland lymphoma, if diagnosed early and treated by combined chemoradiotherapy, carries a good prognosis for survival. The best treatment for thyroid sarcomas and SCC of the thyroid is early diagnosis and aggressive surgery combined with radiotherapy.
散发性和家族性甲状腺髓样癌如果早期发现并通过适当的手术治疗，是一种可治愈的疾病。对RET原癌基因进行基因筛查的出现，为家族性甲状腺髓样癌的早期诊断和治疗带来了巨大希望。新的化疗方案已使转移性甲状腺髓样癌患者出现了一些肿瘤消退。阿霉素的更好应用以及超分割放疗联合减瘤手术延长了未分化甲状腺癌患者的生存期。甲状腺淋巴瘤如果早期诊断并通过放化疗联合治疗，生存预后良好。甲状腺肉瘤和甲状腺鳞状细胞癌的最佳治疗方法是早期诊断、积极手术并联合放疗。
