Bray R J, Woodhams A M, Vallis C J, Kelly P J, Ward-Platt M P
Department of Anaesthesia, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Paediatr Anaesth. 1996;6(2):121-7. doi: 10.1111/j.1460-9592.1996.tb00374.x.
The analgesia provided after major abdominal surgery in 30 children by continuous morphine infusion and patient controlled analgesia, also using morphine, was compared using a double-blind, double-dummy design. The groups of children were comparable in age, weight, duration of operation and sex ratio. Pain assessment was carried out by a single observer using a visual analogue scale and the Poker Chip Tool. Assessments took place during two four-hour periods, one on the day of operation and one the following day. Children aged between nine and 15 years achieved better pain relief with patient controlled analgesia. No difference could be shown in children aged between five and eight years.
采用双盲、双模拟设计，比较了30名儿童在腹部大手术后通过持续输注吗啡和患者自控镇痛（同样使用吗啡）所提供的镇痛效果。儿童组在年龄、体重、手术时长和性别比例方面具有可比性。由一名观察者使用视觉模拟量表和扑克筹码工具进行疼痛评估。评估在两个4小时时间段内进行，一个在手术当天，另一个在第二天。9至15岁的儿童通过患者自控镇痛获得了更好的疼痛缓解。5至8岁的儿童未显示出差异。
