Muff R, Born W, Fischer J A
Department of Orthopedic Surgery, University of Zurich, Switzerland.
Can J Physiol Pharmacol. 1995 Jul;73(7):963-7. doi: 10.1139/y95-133.
Calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin are structurally related polypeptides characterized by a six or seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. They exhibit overlapping biological actions as a result of cross-reactivity between the different receptors. In this article, the respective receptors and G-protein-coupled postreceptor events are reviewed in relation to some of the biological actions of the peptides.
降钙素、降钙素基因相关肽、胰淀素和肾上腺髓质素是结构相关的多肽，其特征在于由二硫键连接的六或七个氨基酸环结构和酰胺化的C末端。由于不同受体之间的交叉反应，它们表现出重叠的生物学作用。在本文中，将结合这些肽的一些生物学作用对各自的受体和G蛋白偶联的受体后事件进行综述。
