Junghardt A, Wildberger H, Török B
Eye Clinic, Kantonsspital, Luzern, Switzerland.
Doc Ophthalmol. 1995;90(3):229-45. doi: 10.1007/BF01203859.
To compare pattern electroretinograms and visual evoked potentials with psychophysical examinations, such as visual acuity, static (automated) perimetry and color vision in unilateral maculopathies of various origins, 20 patients with unilateral retinal diseases within the macula and the posterior pole were tested. Pattern electroretinography, visual evoked potential testing and static perimetry (Octopus program M1) were performed with three different test field sizes (20 degrees x 20 degrees, 10 degrees x 10 degrees and 6 degrees x 6 degrees). The best correlation in all three test field sizes was found between visual acuity, static perimetry and visual evoked potential. This result is surprising, since central area defined functions (visual evoked potentials, visual acuity) correlated well with a total area integrating function (mean defect in static perimetry. The pattern electroretinogram, which seems to reflect an area-related function as well, showed a correlation to static perimetry only in the smaller 10 degrees x 10 degrees and 6 degrees x 6 degrees fields and not a significant correlation in the 20 degrees x 20 degrees field. Smaller stimulation fields may therefore produce sharper results in pattern electroretinographic testing. There was no correlation between pattern electroretinograms and visual evoked potentials or visual acuity. The pattern electroretinogram was recorded under monocular and binocular viewing conditions. In 60% of the patients, the amplitude of the affected eye was more reduced in the monocular than the binocular viewing condition; the healthy fellow eye controlled stable fixation of the affected eye more readily during binocular pattern electroretinogram registration. The degree of the color vision disturbance (C-index, desaturated panel D-15 test) did not correlate to any of the other examinations.
为了将图形视网膜电图和视觉诱发电位与心理物理学检查（如视力、静态（自动）视野检查和色觉）进行比较，在各种病因的单侧黄斑病变中，对20例黄斑和后极部单侧视网膜疾病患者进行了检测。使用三种不同的测试视野大小（20度×20度、10度×10度和6度×6度）进行图形视网膜电图、视觉诱发电位测试和静态视野检查（Octopus程序M1）。在所有三种测试视野大小中，视力、静态视野检查和视觉诱发电位之间的相关性最佳。这一结果令人惊讶，因为中央区域定义功能（视觉诱发电位、视力）与总面积整合功能（静态视野检查中的平均缺损）相关性良好。图形视网膜电图似乎也反映了一种与区域相关的功能，仅在较小的10度×10度和6度×6度视野中与静态视野检查显示出相关性，而在20度×20度视野中无显著相关性。因此，较小的刺激视野可能会在图形视网膜电图测试中产生更清晰的结果。图形视网膜电图与视觉诱发电位或视力之间无相关性。图形视网膜电图是在单眼和双眼观察条件下记录的。在60%的患者中，患眼在单眼观察条件下的振幅比双眼观察条件下降低得更多；在双眼图形视网膜电图记录过程中，健康的对侧眼更容易控制患眼的稳定注视。色觉障碍程度（C指数，不饱和面板D-15测试）与其他任何检查均无相关性。
