Teyke T
Institut für Zoologie (III) Biophysik, Johannes Gutenberg-Universität, Mainz, Germany.
Neurosci Lett. 1996 Mar 8;206(1):29-32. doi: 10.1016/0304-3940(96)12434-4.
The effects of inhibition of nitric oxide (NO) or serotonin (injection of nitro-L-arginine methyl ester (L-NAME) or 5,6-dihydroxytryptamine (5,6-DHT), respectively) on food-attraction conditioning was investigated in Helix. Blocking NO synthase (NOS) prior to conditioning significantly impaired the food-finding ability of the snails. Food-conditioned snails, after inhibition of NOS, remained able to locate the conditioned food. These results indicate that the acquisition of memory depends on NO, whereas memory recall and olfactory orientation are not dependent. Ablating the serotonergic system did not influence food-attraction conditioning, suggesting that food-attraction conditioning may be at variance with conventional associative conditioning procedures.
在蜗牛中研究了抑制一氧化氮（NO）或血清素（分别注射硝基-L-精氨酸甲酯（L-NAME）或5,6-二羟基色胺（5,6-DHT））对食物吸引条件作用的影响。在条件作用之前阻断一氧化氮合酶（NOS）会显著损害蜗牛寻找食物的能力。在抑制NOS后，经食物条件化的蜗牛仍能够找到条件化的食物。这些结果表明，记忆的获得依赖于NO，而记忆回忆和嗅觉定向则不依赖于NO。切除血清素能系统并未影响食物吸引条件作用，这表明食物吸引条件作用可能与传统的联想条件作用程序不同。
