Ikura M
Division of Molecular and Structural Biology, Ontario Cancer Institute, Canada.
Trends Biochem Sci. 1996 Jan;21(1):14-7.
EF-hand proteins undergo conformational changes upon binding of Ca2+. This event is a crucial step in many Ca2+-dependent cellular processes. Recent advances in the three-dimensional structural analysis of various EF-hand proteins have led to new insights into the structure and functional relationship of this large family of Ca2+-binding proteins.
EF 手型蛋白在结合 Ca2+ 后会发生构象变化。这一事件是许多依赖 Ca2+ 的细胞过程中的关键步骤。各种 EF 手型蛋白三维结构分析的最新进展为这个大家族的 Ca2+ 结合蛋白的结构与功能关系带来了新的见解。
