一氧化氮生成化合物对脑心肌炎病毒的活性。
Activity of nitric oxide-generating compounds against encephalomyocarditis virus.
作者信息
Guillemard E, Geniteau-Legendre M, Kergot R, Lemaire G, Petit J F, Labarre C, Quero A M
机构信息
Laboratoire de Virologie et Immunologie Expérimentales, Centre d'Etudes Pharmaceutiques de Châtenay-Malabry, France.
出版信息
Antimicrob Agents Chemother. 1996 Apr;40(4):1057-9. doi: 10.1128/AAC.40.4.1057.
Abstract
Nitric oxide (NO) generated by two NO donors (sodium nitroprusside or S-nitroso-L-glutathione) was shown to exert a dose-dependent inhibition of encephalomyocarditis virus growth in L-929 cells. This activity was not due to the cytotoxic or direct virucidal effects of NO donors. L-929 cells were shown to produce NO endogenously, but this low level of production did not counter encephalomyocarditis virus replication.
摘要
两种一氧化氮供体（硝普钠或S-亚硝基-L-谷胱甘肽）产生的一氧化氮（NO）对脑心肌炎病毒在L-929细胞中的生长具有剂量依赖性抑制作用。该活性并非由于一氧化氮供体的细胞毒性或直接杀病毒作用。研究表明L-929细胞可内源性产生NO，但这种低水平的产生并不能对抗脑心肌炎病毒的复制。
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J Clin Invest. 1993 Jun;91(6):2446-52. doi: 10.1172/JCI116479.
2
3
Coinduction of nitric oxide synthesis and intracellular nonheme iron-nitrosyl complexes in murine cytokine-treated fibroblasts.
Free Radic Biol Med. 1994 Jun;16(6):869-70. doi: 10.1016/0891-5849(94)90206-2.
4
Macrophage response to viruses, protozoa, and fungi: secretory and cellular activities induced in resting unprimed bone marrow-derived mononuclear phagocytes.巨噬细胞对病毒、原生动物和真菌的反应：静息未致敏骨髓来源的单核吞噬细胞诱导的分泌和细胞活性
Cell Immunol. 1994 Dec;159(2):323-30. doi: 10.1006/cimm.1994.1318.
5
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Science. 1993 Sep 10;261(5127):1445-8. doi: 10.1126/science.7690156.
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