Brown A G
Biotics Limited, University of Sussex, Brighton.
Folia Microbiol (Praha). 1995;40(1):31-42. doi: 10.1007/BF02816526.
Modern trends in the detection, isolation and characterization of leads for novel therapeutic compounds are reviewed. Some current biological test systems (immunological, chemical, enzymic, receptor, etc.) and examples of their successful application are highlighted including the structures of selected novel and prospective metabolites.
本文综述了新型治疗化合物先导物的检测、分离和表征的现代趋势。重点介绍了一些当前的生物测试系统(免疫、化学、酶、受体等)及其成功应用的实例,包括选定的新型和潜在代谢物的结构。