Kohnen P W, Drach G W
J Urol. 1979 Jun;121(6):755-60. doi: 10.1016/s0022-5347(17)56980-3.
In a series of 162 cases of surgically resected hyperplastic prostates the incidence of inflammation is 98.1%. Six morphologic patterns of inflammation are described: 1) segregated glandular inflammation, 2) periglandular inflammation, 3) diffuse stromal inflammation, 4) isolated stromal lymphoid nodules, 5) acute necrotizing inflammation and 6) focal granulomatous inflammation. The most common pattern, segregated glandular inflammation, is characterized by intraluminal neutrophils and foamy macrophages and by chronic inflammatory cells in the surrounding stroma. No significant morphological differences are found among groups of cases with positive and negative evidence by culture of bacterial prostatic infection. Quantitative but not qualitative morphologic differences are found between cases of gram-negative infections and infection by gram-positive organisms that often are considered non-pathogens.
在一系列162例手术切除的增生性前列腺病例中，炎症发生率为98.1%。描述了六种炎症形态模式：1）分离性腺管炎症，2）腺管周围炎症，3）弥漫性间质炎症，4）孤立性间质淋巴小结，5）急性坏死性炎症和6）局灶性肉芽肿性炎症。最常见的模式，即分离性腺管炎症，其特征是管腔内有中性粒细胞和泡沫状巨噬细胞，周围间质中有慢性炎症细胞。在前列腺细菌感染培养有阳性和阴性证据的病例组之间未发现明显的形态学差异。在革兰氏阴性菌感染病例与通常被认为是非病原体的革兰氏阳性菌感染病例之间发现了数量上而非质量上的形态学差异。
