Medalion B, Merin G, Elami A, Milgalter E, Rudis E, Deviri E, Anner H, Wolf Y, Eidelman L A, Mosseri M, Schechter D, Berlatzky Y
Dept. of Cardiothoracic Surgery, Hadassah-University Hospital, Jerusalem.
Harefuah. 1996 Aug;131(3-4):79-82, 144.
The optimal surgical treatment for concomitant carotid and coronary artery disease is controversial. Between 1991 and 1995 we performed 34 procedures for combined disease of the carotid and coronary arteries. The first 8 operations were carotid endarterectomies followed by coronary artery bypass grafting (staged procedure). The next 26 operations were performed during a single anesthesia (combined procedure). The patients were 28 men and 6 women, aged 58-81 years (mean 68). 80% were in functional class III or IV. In 40% ventricular function was moderately or severely reduced. There was an average of 3.6 grafts per patient, and in all except 3 patients the left internal thoracic artery was used as a conduit for coronary artery bypass grafting. 30% had symptomatic carotid stenosis; there was no perioperative mortality. In the staged procedure group, 2 patients had postoperative cardiac complications: in 1 acute coronary insufficiency and acute myocardial infarction in the other. 1 had postoperative, transient, amaurosis fugax. In the combined procedure group, 1 had a myocardial infarction and 1 a minor occipital stroke. During follow-up, 1 patient died 4 months after operation of myocardial infarction, and 1 had a minor stroke. The results suggest that the combined procedure is safe and carries low risk of both mortality and morbidity. Whenever cardiac disease is stable and there is no main coronary artery disease, a staged procedure should be considered. In any other situation we continue to perform the combined procedure.
颈动脉和冠状动脉疾病的最佳手术治疗方法存在争议。1991年至1995年间,我们对34例颈动脉和冠状动脉合并疾病患者进行了手术。前8例手术为先进行颈动脉内膜切除术,然后进行冠状动脉旁路移植术(分期手术)。接下来的26例手术在一次麻醉下完成(联合手术)。患者中男性28例,女性6例,年龄58 - 81岁(平均68岁)。80%的患者心功能分级为Ⅲ级或Ⅳ级。40%的患者心室功能中度或重度降低。每位患者平均植入3.6根移植血管,除3例患者外,均使用左胸廓内动脉作为冠状动脉旁路移植的血管桥。30%的患者有症状性颈动脉狭窄;围手术期无死亡病例。在分期手术组,2例患者术后出现心脏并发症:1例发生急性冠状动脉供血不足,另1例发生急性心肌梗死。1例患者术后出现短暂性黑矇。在联合手术组,1例发生心肌梗死,1例发生轻微枕叶卒中。随访期间,1例患者术后4个月死于心肌梗死,1例发生轻微卒中。结果表明,联合手术是安全的,死亡率和发病率风险均较低。只要心脏病病情稳定且无主要冠状动脉疾病,应考虑分期手术。在任何其他情况下,我们继续采用联合手术。