Yoshida T, Osato H, Sakon M, Monden T, Amano M, Aoki T, Kishimoto S, Umeshita K, Dono K, Gotoh M, Monden M
Dept. of Surgery II, Osaka University Medical School.
Gan To Kagaku Ryoho. 1996 Sep;23(11):1575-7.
We performed the locoregional injection of OK-432/fibrinogen/thrombin to unresectable hepatic tumors metastasized from colorectal cancers, which were hardly controlled by arterial infusion chemotherapy. CEA was markedly decreased following this treatment, although abdominal CT did not show a significant reduction of tumor mass. This immuno-injection therapy may be a choice of treatment for metastatic liver tumors, refractory to treatment by conventional chemotherapy.
我们对无法切除的、由结直肠癌转移而来且难以通过动脉灌注化疗控制的肝肿瘤进行了局部区域注射OK-432/纤维蛋白原/凝血酶治疗。尽管腹部CT显示肿瘤体积无明显缩小，但治疗后癌胚抗原显著降低。这种免疫注射疗法可能是传统化疗难治性转移性肝肿瘤的一种治疗选择。
