• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于双等位基因BW4 - BW6系统的HLA - BW35异质性。

Heterogeneity of HLA-BW35 based on the diallelic BW4-BW6 system.

作者信息

DeGoey S R, Moore S B, Watts S K, Radue V A, Testin J

出版信息

Mayo Clin Proc. 1979 Aug;54(8):527-30.

PMID:88551
Abstract

Utilizing the diallelic BW4-BW6 system of antigens and antibodies, we divided subjects possessing HLA-BW35 into two groups, depending on the association of their BW35 antigens with BW4 or BW6, and demonstrated in family studies that the associated antigens appeared to be inherited together. Absorption experiments were performed to establish the validity of the typings. Anti-human beta2-microglobulin was used in an effort to "map" the location of the BW4 and BW6 antigenic determinants on the HLA molecule.

摘要

利用等位基因BW4 - BW6抗原和抗体系统,我们根据HLA - BW35抗原与BW4或BW6的关联,将拥有HLA - BW35的受试者分为两组,并在家族研究中证明相关抗原似乎是一起遗传的。进行吸收实验以确定分型的有效性。使用抗人β2 - 微球蛋白来“定位”HLA分子上BW4和BW6抗原决定簇的位置。

相似文献

1
Heterogeneity of HLA-BW35 based on the diallelic BW4-BW6 system.基于双等位基因BW4 - BW6系统的HLA - BW35异质性。
Mayo Clin Proc. 1979 Aug;54(8):527-30.
2
Bw4-reactive and Bw6-reactive antibodies recognize multiple distinct HLA structures that partially overlap in the alpha-1 helix.Bw4反应性抗体和Bw6反应性抗体识别多种不同的HLA结构,这些结构在α-1螺旋中部分重叠。
J Immunol. 1994 Nov 1;153(9):4099-110.
3
Characterization of a monoclonal anti-Bw4 antibody (Tü109): evidence for similar epitopes on the Bw4 and Bw6 antigens.一种抗Bw4单克隆抗体(Tü109)的特性:Bw4和Bw6抗原上相似表位的证据
Hum Immunol. 1985 Dec;14(4):333-49. doi: 10.1016/0198-8859(85)90241-1.
4
The primary structure of HLA-A32 suggests a region involved in formation of the Bw4/Bw6 epitopes.HLA - A32的一级结构表明存在一个参与Bw4/Bw6表位形成的区域。
J Immunol. 1986 Dec 1;137(11):3671-4.
5
The structure and evolution of the HLA--Bw4 and Bw6 antigens.HLA-Bw4和Bw6抗原的结构与演变
Tissue Antigens. 1979 May;13(5):334-41. doi: 10.1111/j.1399-0039.1979.tb00805.x.
6
[Heterogeneity of HLA-Bw-35 and HLA-B12 antigens demonstrated by complex sera of anti-HLA-Bw4 and anti-HLA-Bw6].[抗HLA - Bw4和抗HLA - Bw6复合血清所显示的HLA - Bw35和HLA - B12抗原的异质性]
Vnitr Lek. 1984 May;30(5):497-501.
7
HLA antigens of platelets. IV. Influence of "private" HLA--B locus specificities on the expression of Bw4 and Bw6 on human platelets.
Tissue Antigens. 1980 Apr;15(4):361-8. doi: 10.1111/j.1399-0039.1980.tb00196.x.
8
A monoclonal antibody directed against the HLA-Bw6 epitope.一种针对HLA - Bw6表位的单克隆抗体。
J Immunol. 1982 Jun;128(6):2804-6.
9
Antigenic determinants of the HLA-B7 molecule; Bw6- and B7-specific determinants are spatially separate.HLA - B7分子的抗原决定簇;Bw6特异性决定簇和B7特异性决定簇在空间上是分开的。
Immunogenetics. 1983;18(1):1-16. doi: 10.1007/BF00401351.
10
Human leukocyte antigen Bw4 and Bw6 epitopes recognized by antibodies and natural killer cells.抗体和自然杀伤细胞识别的人类白细胞抗原Bw4和Bw6表位
Curr Opin Organ Transplant. 2014 Aug;19(4):436-41. doi: 10.1097/MOT.0000000000000103.

引用本文的文献

1
HLA- and H-2-associated variations of intra- and extracellular magnesium content.HLA和H-2相关的细胞内和细胞外镁含量变化
Proc Natl Acad Sci U S A. 1990 Mar;87(5):1894-8. doi: 10.1073/pnas.87.5.1894.