Sher R, Mackay M E, Macnab G M, Kok S H, Koornhof H J
Infect Immun. 1977 Jul;17(1):1-3. doi: 10.1128/iai.17.1.1-3.1977.
The prevalence of hepatitis B antigen (HBsAg), hepatitis B antibody (HBsAb), and subtypes in 242 cases of leprosy is reported. Patients were divided into three subgroups, lepromatous (174), tuberculoid (55), and borderline (13). A total of 131 patients were tested on admission; the remaining 111 had been institutionalized for a period of 3 months or more when tested. Of the 131 cases tested on admission, 88 were retested 6 to 12 months after admission. There was no statistical difference in the incidence of HBsAg and HBsAb among the three groups or between normal controls and the leprosy patients. The predominant subtype was ADW (84.1%). After institutionalization, one lepromatous case converted to HBsAg positive and four converted to HBsAb positive.
报告了242例麻风病患者中乙肝抗原(HBsAg)、乙肝抗体(HBsAb)及其亚型的流行情况。患者分为三个亚组,瘤型(174例)、结核样型(55例)和界线类(13例)。共有131例患者在入院时接受检测;其余111例在入院3个月或更长时间后接受检测时已住院治疗。在入院时接受检测的131例病例中,88例在入院6至12个月后再次接受检测。三组之间以及正常对照与麻风病患者之间HBsAg和HBsAb的发生率无统计学差异。主要亚型为ADW(84.1%)。住院治疗后,1例瘤型病例转为HBsAg阳性,4例转为HBsAb阳性。