Cohen J I
National Institutes of Health, Bethesda, Maryland, USA.
Infect Dis Clin North Am. 1996 Sep;10(3):457-68. doi: 10.1016/s0891-5520(05)70308-1.
Varicella-zoster virus (VZV) causes chickenpox and herpes zoster. After acute infection the virus becomes latent in dorsal root and trigeminal ganglia for the lifetime of the individual. The viral genome encodes about 70 proteins, at least three of which are thought to be expressed during latency in humans. VZV grows in cell culture, but is very cell-associated; it is relatively difficult to obtain high titers of cell-free virus.
水痘带状疱疹病毒(VZV)可引起水痘和带状疱疹。急性感染后,该病毒会在背根神经节和三叉神经节中潜伏,伴随个体一生。病毒基因组编码约70种蛋白质,其中至少有三种被认为在人类潜伏期间表达。VZV可在细胞培养中生长,但与细胞紧密相关;获得高滴度的无细胞病毒相对困难。