Altomare G F, Capella G L, Frigerio E
Instituto di Dermatologia, Ospedale Maggiore IRCCS, Universita degli Studi di Milano, Italy.
Clin Exp Dermatol. 1995 Nov;20(6):502-3. doi: 10.1111/j.1365-2230.1995.tb01389.x.
Erythema annulare centrifugum (EAC), a disease belonging to the poorly characterized category of 'figurate erythemas', has been associated with a variety of conditions, such as connective tissue diseases, infections, neoplasms and drug reactions. Here we report a case of EAC associated with sarcoidosis, the first case in the literature to our knowledge. EAC was the sole sign of the granulomatous disease process, which was diagnosed by means of appropriate investigations only after the patient reported the sudden resolution of a long-standing sensitization to perfumes and parabens. Steroid treatment for sarcoidosis improved the patient's condition, and restored the allergic response to these substances.
离心性环状红斑（EAC）属于“环状红斑”这一特征不明的疾病类别，与多种情况相关，如结缔组织病、感染、肿瘤和药物反应。在此我们报告一例与结节病相关的EAC病例，据我们所知这是文献中的首例。EAC是肉芽肿性疾病过程的唯一体征，仅在患者报告对香水和对羟基苯甲酸酯的长期致敏突然消退后，通过适当检查才得以诊断。针对结节病的类固醇治疗改善了患者状况，并恢复了对这些物质的过敏反应。
