Horak F, Stark H
HNO. 1977 Jun;25(6):222-4.
Detailed histories of 20 patients with suspected hay fever were prepared from questionnaires. These patients were skin-tested with allergens prepared form four different grass mixtures, and a nasal provocative test with a fifth grass preparation was utilized. This latter test was evaluated by the clinical reaction of the nasal mucous membrane, by measuring the temperature variations in the nasal lumen, and by determining the nasal resistance with the use of "passive anterior rhinomanometry" (P.A.R.). In addition, the total serum IgE level and three grass-specific IgE concentrations were determined. The following results were then found: eight patients were consistently positive and four patients were consistently negative in all tests for allergens. Among the remaining eight patients, two false-positive and six false-negative patients by skin tests were uncovered by the additional use of history, IgE determinations and the nasal provocative test with rhinomanometric evaluation.
通过问卷调查收集了20例疑似花粉热患者的详细病史。用由四种不同草混合物制备的过敏原对这些患者进行皮肤试验,并使用第五种草制剂进行鼻腔激发试验。通过鼻黏膜的临床反应、测量鼻道内的温度变化以及使用“被动前鼻测压法”(P.A.R.)测定鼻阻力来评估后一项试验。此外,还测定了总血清IgE水平和三种草特异性IgE浓度。结果发现:8例患者在所有过敏原检测中均持续呈阳性,4例患者均持续呈阴性。在其余8例患者中,通过进一步利用病史、IgE测定以及带有鼻测压评估的鼻腔激发试验,发现了2例假阳性和6例假阴性的皮肤试验患者。