Jessup J M, Menck H R, Winchester D P, Hundahl S A, Murphy G P
Department of Surgery, New England Deaconess Hospital, Boston, Massachusetts, USA.
Cancer. 1996 Oct 15;78(8):1829-37. doi: 10.1002/(sici)1097-0142(19961015)78:8<1829::aid-cncr26>3.0.co;2-z.
Previous Commission on Cancer data from the National Cancer Data Base (NCDB) have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data are described here.
Five calls for data have yielded a total of 3,700,000 cases for the years 1985 through 1993, including 477,679 cases for 1988, and 608,593 cases for 1993, from hospital cancer registries across the U.S.
The most recent call for data for 1993 comprised 52% of the estimated new cases of cancer in the U.S. The country was comprised of 6 regions, with the Mountain and Southeast regions having the highest regional reporting of new cases of cancer (69% and 55%, respectively) and the Northeast and Pacific regions having the lowest (47% each). Approximately 96% of patients received their treatment at the reporting hospital. The 4 most common carcinomas were breast (15.7%), lung (14.6%), prostate (14.2%), and colon (7.5%) and comprised the majority of new cases. Trends in patterns of care for breast carcinoma were analyzed for possible bias in the 1988 and 1993 periods. When hospitals reporting only in 1988 or in 1993 were compared with hospitals reporting at both time points, the only differences were small differences in ethnic participation. These differences were less than 1.5% in the proportion of African Americans reported in the different time periods. There were no significant differences in the downstaging of breast carcinoma, or the role of conservative surgery or adjuvant radiation therapy.
The NCDB is a cancer management and outcomes data base for health care organizations that presently comprises 52% of the estimated new cases in the U.S. This will increase to 80% as the approved hospitals of the Commission on Cancer are required to report to the NCDB. Comparison of breast carcinoma findings at two time periods appeared similar regardless of hospital reporting set (i.e., set of hospitals reporting for one period versus both periods).
国家癌症数据库（NCDB）以往的癌症委员会数据研究了特定癌症在疾病分期、治疗模式和生存率方面的时间趋势。本文介绍的是最新（1993年）的数据。
五次数据征集共获得了1985年至1993年期间的370万例病例，其中包括1988年的477,679例和1993年的608,593例，数据来自美国各地的医院癌症登记处。
1993年最近一次数据征集涵盖了美国估计新增癌症病例的52%。美国分为6个地区，山区和东南部地区新癌症病例的区域报告率最高（分别为69%和55%），东北部和太平洋地区最低（均为47%）。约96%的患者在报告医院接受治疗。四种最常见的癌症是乳腺癌（15.7%）、肺癌（14.6%）、前列腺癌（14.2%）和结肠癌（7.5%），它们占新病例的大多数。分析了1988年和1993年期间乳腺癌治疗模式的趋势，以探讨可能存在的偏差。当仅在1988年或1993年报告的医院与在两个时间点都报告的医院进行比较时，唯一的差异是种族参与度的细微差别。不同时间段报告的非裔美国人比例差异小于1.5%。乳腺癌分期下调、保乳手术或辅助放疗的作用方面没有显著差异。
NCDB是一个面向医疗保健机构的癌症管理和结局数据库，目前涵盖美国估计新增病例的52%。随着癌症委员会批准的医院被要求向NCDB报告，这一比例将增至80%。无论医院报告组如何（即一个时间段报告的医院组与两个时间段都报告的医院组），两个时间段乳腺癌的研究结果比较似乎都相似。
