Xianghuai L, Zhihong Z, Zhuyao Z, Nan H, Ping Y, Guanjun C
Ion Beam Laboratory, Shanghai Institute of Metallurgy, Chinese Academy of Sciences, P. R. China.
J Biomater Appl. 1996 Apr;10(4):330-7. doi: 10.1177/088532829601000403.
Ion beam enhanced deposition (IBED) was adopted to synthesize biocompatible titanium oxide film. Structure characteristics of titanium oxide film were investigated by RBS, AES, and XRD. The blood compatibility of the titanium oxide film was studied by measurements of blood clotting time and platelet adhesion. The results show that the anticoagulation property of titanium oxide film is improved significantly. The mechanism of anticoagulation of the titanium oxide film was discussed.