Golubovic S, Latkovic Z, Horvatic-Obradovic M
University Eye Hospital, Belgrade, Pasterova, Yugoslavia.
Doc Ophthalmol. 1995;91(1):25-32. doi: 10.1007/BF01204621.
Corneal and limbal dermoids are uncommon choristomatous corneal tumors. They clinically present as round or oval, whitish or yellowish cones protruding on the anterior surface of the eyeball. They are composed of ectodermal (keratinized epithelium, hairs, sebaceous and sudoriferous glands, nerves, smooth muscles and, less frequently, teeth) and mesodermal elements (fibrous tissue, fat, blood vessels and cartilage) combined in different proportion. If fat dominates in histology of the tumor, it is called a lipodermoid. A case of a two-year old boy with a large corneal dermoid on the right eye is presented. Dermoid covered almost the whole cornea and was associated with adherence of the atrophic iris to the posterior corneal surface and partial congenital cataract. Surgical therapy included excision of dermoid together with the superficial lamellae of the corneal stroma and penetrating keratoplasty. Satisfactory tectonic and esthetic outcome was achieved and has been maintained for four postoperative years now.
角膜和角膜缘皮样瘤是罕见的迷芽瘤性角膜肿瘤。临床上表现为圆形或椭圆形、白色或淡黄色的圆锥体,突出于眼球前表面。它们由外胚层(角化上皮、毛发、皮脂腺和汗腺、神经、平滑肌,较少见牙齿)和中胚层成分(纤维组织、脂肪、血管和软骨)以不同比例组合而成。如果肿瘤组织学中脂肪占主导,则称为脂质皮样瘤。本文报告一例两岁男孩右眼巨大角膜皮样瘤的病例。皮样瘤几乎覆盖整个角膜,并伴有萎缩性虹膜与角膜后表面粘连及部分先天性白内障。手术治疗包括切除皮样瘤及角膜基质浅层,并进行穿透性角膜移植术。术后获得了满意的结构和美学效果,至今已维持四年。