Sharon P, Kaplinsky N, Leiba S, Frankl O
J Rheumatol. 1977 Spring;4(1):73-5.
Aseptic necrosis of bone is a known complication of corticosteroid therapy. We report a case of aseptic necrosis of the femoral head as a presenting symptom of Cushing's disease. The case demonstrates that endogenous steroids, like exogenous steroids, may bear the same relationship to the pathogenesis of aseptic necrosis of bone. It also indicates that Cushing's disease must be considered in every case of so-called idiopathic aseptic necrosis of bone.
骨无菌性坏死是皮质类固醇治疗已知的并发症。我们报告一例股骨头无菌性坏死作为库欣病的首发症状。该病例表明,内源性类固醇与外源性类固醇一样,可能与骨无菌性坏死的发病机制存在相同的关系。这也表明,在每一例所谓的特发性骨无菌性坏死病例中都必须考虑库欣病。