Rudzinski W E, Norman S, Dahlquist B, Greebon K W, Richardson A, Locke K, Thomas T
Department of Chemistry, Southwest Texas State University, San Marcos 78666, USA.
Am Ind Hyg Assoc J. 1996 Oct;57(10):914-7. doi: 10.1080/15428119691014422.
A new reagent, 1-(9-anthracenylmethyl)piperzine (MAP), was used for the derivatization of airborne 1,6-hexamethylene diisocyanate (HDI) and polyisocyanates generated during spray-painting operations. The new reagent, which offers enhanced sensitivity and uniformity of response to both the monomeric and oligomeric forms of HDI, was compared directly with 1-(2-methoxyphenyl)piperazine (MOP), the currently employed derivatizing reagent used in the National Institute for Occupational Safety and Health Method 5521. Both the validity of the side-by-side sampling protocol and the efficacy of two derivatizing reagents were evaluated in field studies. The analytical results indicate that there is no significant difference at the 95% confidence level in the concentration of polyisocyanate in the aerosol as determined by two impingers containing MAP and a third containing MOP when these are positioned in a side-by-side-by-side arrangement.
一种新型试剂1-(9-蒽甲基)哌嗪（MAP）用于对喷漆作业过程中产生的空气中的1,6-六亚甲基二异氰酸酯（HDI）和多异氰酸酯进行衍生化。将这种对HDI的单体和低聚体形式均具有更高灵敏度和响应一致性的新型试剂，与美国国家职业安全与健康研究所方法5521中目前使用的衍生化试剂1-(2-甲氧基苯基)哌嗪（MOP）进行了直接比较。在现场研究中评估了并排采样方案的有效性和两种衍生化试剂的功效。分析结果表明，当三个冲击式吸收管以并排排列方式放置，其中两个装有MAP，另一个装有MOP时，在95%置信水平下，由它们测定的气溶胶中多异氰酸酯浓度没有显著差异。
