Yatsu Y, Yoshida H, Araki I, Shirasaki S, Miyata A, Maeda A, Matsuki A
Department of Anesthesiology, Hachinohe City Hospital.
Masui. 1996 Feb;45(2):200-4.
The effect of preoperative oral fluid intake on the volume and pH of gastric fluid was examined in 45 elective surgical patients ranged in ages from 18 to 70 years. Two hours preoperatively they all received oral roxatidine 75 mg with 10 ml water, immediately followed by 150 ml oral water or 150 ml refreshing drink or no fluid as control. Just after the induction of anesthesia, a Salem-sump tube was put down to the stomach to collect gastric fluid in each patient. The volume and pH of gastric fluid taken were 10.9 +/- 7.9 ml, 16.3 +/- 2.3 in control group, 8.0 +/- 6.0 ml, 6.2 +/- 2.4 in the water group and 6.3 +/- 6.0 ml, 7.1 +/- 1.7 in the refreshing drink group. As there were no significant differences in gastric pH values in the three groups, the highest value was found in the refreshing drink group. No significant difference in VAS of hungry and thirsty feeling was found among the three groups. We conclude that preoperative oral water or refreshing drink with roxatidine 75 mg 2 hours before the start of anesthesia may not increase the risk of aspiration during the induction of anesthesia.
对45例年龄在18至70岁之间的择期手术患者，研究了术前口服液体摄入对胃液容量和pH值的影响。术前两小时，他们均口服75毫克罗沙替丁并饮用10毫升水，随后立即饮用150毫升水或150毫升清凉饮料，或不摄入液体作为对照。麻醉诱导后，立即为每位患者插入一根塞勒姆双腔胃管以收集胃液。对照组胃液的容量和pH值分别为10.9±7.9毫升、16.3±2.3，水组为8.0±6.0毫升、6.2±2.4，清凉饮料组为6.3±6.0毫升、7.1±1.7。由于三组胃液pH值无显著差异，清凉饮料组的值最高。三组在饥饿和口渴感的视觉模拟评分上无显著差异。我们得出结论，麻醉开始前两小时口服水或含75毫克罗沙替丁的清凉饮料可能不会增加麻醉诱导期间误吸的风险。
