Doughty J C, McCarter D H, Kane E, Reid A W, Cooke T G, McArdle C S
Department of Surgery, Glasgow Royal Infirmary, UK.
Br J Surg. 1996 Aug;83(8):1128-30. doi: 10.1002/bjs.1800830830.
Twenty-eight patients with locally advanced breast cancer received four doses of regional chemotherapy via angiographically placed percutaneous catheters into the internal mammary artery (IMA) and lateral thoracic artery. Patent blue dye was injected to outline the relative contribution to perfusion of each of these vessels. The IMA was found to perfuse 67 (range 20-95) per cent of the breast and the lateral thoracic artery 15 (range 0-35) per cent. In 33 per cent of patients the lateral thoracic artery did not contribute to breast perfusion and a large area of the lateral aspect of the breast was perfused from a further branch of the subclavian or axillary artery. The blood supply to the breast is extremely variable and must be determined in each patient before delivering regional chemotherapy.
28例局部晚期乳腺癌患者通过经皮导管在血管造影引导下置于胸廓内动脉（IMA）和胸外侧动脉，接受了4次区域化疗。注射专利蓝染料以勾勒出这些血管中每一根对灌注的相对贡献。发现IMA灌注乳房的67%（范围20 - 95%），胸外侧动脉灌注15%（范围0 - 35%）。在33%的患者中，胸外侧动脉对乳房灌注无贡献，乳房外侧的大片区域由锁骨下动脉或腋动脉的另一分支灌注。乳房的血液供应差异极大，在进行区域化疗前必须为每位患者确定其血液供应情况。
