Fuse T, Takagi T, Fukushima T, Hashimoto N, Yamada K
Department of Neurosurgery, Nagoya City Higashi General Hospital, Japan.
Childs Nerv Syst. 1996 Jul;12(7):404-8. doi: 10.1007/BF00395095.
The first case of a child with an arteriovenous malformation (AVM) associated with moyamoya disease is reported. The patient presented ischemic symptoms and underwent indirect bypass surgery on both sides when she was 5 years old. Four years later she suffered from headache, and a small AVM of the left frontal lobe associated with the moyamoya vessels was detected. Single photon emission computed tomography (SPECT) was performed at age 11 and demonstrated low local cerebral blood flow (CBF) in the left frontal lobe and right temporal lobe, although the revascularization after the bypass surgery seemed to be effective, as judged on pancerebral angiography. We feel that brain ischemia due to the moyamoya disease may have played a causative role in the development of the AVM.
本文报告了首例患有与烟雾病相关的动静脉畸形（AVM）的儿童病例。该患者出现缺血症状，5岁时接受了双侧间接搭桥手术。四年后，她出现头痛症状，检测发现左额叶有一个与烟雾病血管相关的小型AVM。患者11岁时进行了单光子发射计算机断层扫描（SPECT），结果显示左额叶和右颞叶局部脑血流量（CBF）较低，尽管根据全脑血管造影判断，搭桥手术后的血管重建似乎是有效的。我们认为，烟雾病导致的脑缺血可能在AVM的发生发展中起到了致病作用。
