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白屈菜(罂粟科)的药理活性。

Pharmacological activities of Chelidonium majus L. (Papaveraceae).

作者信息

Colombo M L, Bosisio E

机构信息

Institute of Pharmacological Sciences, University of Milan, Italy.

出版信息

Pharmacol Res. 1996 Feb;33(2):127-34. doi: 10.1006/phrs.1996.0019.

DOI:10.1006/phrs.1996.0019
PMID:8870028
Abstract

Chelidonium majus L. (Papaveraceae) has a long history as being useful for the treatment of many diseases in European countries. This plant is of great interest for its use also in Chinese herbal medicine. The plant contains, as major secondary metabolites, isoquinoline alkaloids, such as sanguinarine, chelidonine, chelerythrine, berberine and coptisine. Other compounds structurally unrelated to the alkaloids have been isolated from the aerial parts: several flavonoids and phenolic acids. C. majus extracts and its purified compounds exhibit interesting antiviral, antitumour and antimicrobial properties both in vitro and in vivo.

摘要

白屈菜(罂粟科)在欧洲国家作为治疗多种疾病的药物有着悠久的历史。这种植物在中国草药中也因其用途而备受关注。该植物主要的次生代谢产物为异喹啉生物碱,如血根碱、白屈菜碱、白屈菜红碱、小檗碱和黄连碱。从地上部分还分离出了其他与生物碱结构无关的化合物:几种黄酮类化合物和酚酸。白屈菜提取物及其纯化化合物在体外和体内均表现出有趣的抗病毒、抗肿瘤和抗菌特性。

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