Houghton L A, Heyman D J, Whorwell P J
Department of Medicine, University Hospital of South Manchester, UK.
Aliment Pharmacol Ther. 1996 Feb;10(1):91-5. doi: 10.1111/j.1365-2036.1996.tb00181.x.
The purposes of this study were to quantify the effects of severe irritable bowel syndrome on quality of life and economic functioning, and to assess the impact of hypnotherapy on these features.
A validated quality of life questionnaire including questions on symptoms, employment and health seeking behaviour was administered to 25 patients treated with hypnotherapy (aged 25-55 years; four male) and to 25 control irritable bowel syndrome patients of comparable severity (aged 21-58 years; two male). Visual analogue scales were used and scores derived to assess the patients' symptoms and satisfaction with each aspect of life.
Patients treated with hypnotherapy reported less severe abdominal pain (P < 0.0001), bloating (P < 0.02), bowel habit (P < 0.0001), nausea (P < 0.05), flatulence (P < 0.05), urinary symptoms (P < 0.01), lethargy (P < 0.01), backache (P = 0.05) and dyspareunia (P = 0.05) compared with control patients. Quality of life, such as psychic well being (P < 0.0001), mood (P < 0.001), locus of control (P < 0.05), physical well being (P < 0.001) and work attitude (P < 0.001) were also favourably influenced by hypnotherapy. For those patients in employment, more of the controls were likely to take time off work (79% vs. 32%; p = 0.02) and visit their general practitioner ( 58% vs. 21%; P = 0.056) than those treated with hypnotherapy. Three of four hypnotherapy patients out of work prior to treatment resumed employment compared with none of the six in the control group.
This study has shown that in addition to relieving the symptoms of irritable bowel syndrome, hypnotherapy profoundly improves the patients' quality of life and reduces absenteeism from work. It therefore appears that, despite being relatively expensive to provide, it could well be a good long-term investment.
本研究旨在量化重度肠易激综合征对生活质量和经济功能的影响，并评估催眠疗法对这些特征的影响。
对25例接受催眠疗法的患者（年龄25 - 55岁；4例男性）和25例病情严重程度相当的对照肠易激综合征患者（年龄21 - 58岁；2例男性）进行了一份经过验证的生活质量问卷调查，问卷包括有关症状、就业和就医行为的问题。使用视觉模拟量表并得出分数，以评估患者的症状以及对生活各个方面的满意度。
与对照患者相比，接受催眠疗法的患者报告的腹痛（P < 0.0001）、腹胀（P < 0.02）、排便习惯（P < 0.0001）、恶心（P < 0.05）、肠胃胀气（P < 0.05）、泌尿系统症状（P < 0.01）、无精打采（P < 0.01）、背痛（P = 0.05）和性交困难（P = 0.05）症状较轻。催眠疗法对生活质量也有积极影响，如心理健康（P < 0.0001）、情绪（P < 0.001）、控制感（P < 0.05）、身体健康（P < 0.001）和工作态度（P < 0.001）。对于那些有工作的患者，与接受催眠疗法的患者相比，更多的对照患者可能会请假（79% 对32%；p = 0.02）并去看全科医生（58% 对21%；P = 0.056）。治疗前失业的4例接受催眠疗法的患者中有3例恢复了工作，而对照组的6例患者中无一恢复工作。
本研究表明，催眠疗法除了能缓解肠易激综合征的症状外，还能显著改善患者的生活质量并减少旷工。因此，尽管提供催眠疗法的成本相对较高，但它很可能是一项不错的长期投资。
