Riehl M E, Pandolfino J E, Palsson O S, Keefer L
Division of Gastroenterology and Hepatology, Esophageal Center at Northwestern, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Dis Esophagus. 2016 Jul;29(5):490-6. doi: 10.1111/dote.12353. Epub 2015 Mar 30.
Functional heartburn (FH) is a benign but burdensome condition characterized by painful, burning epigastric sensations in the absence of acid reflux or symptom-reflux correlation. Esophageal hypersensitivity and its psychological counterpart, esophageal hypervigilance (EHv) drive symptom experience. Hypnotherapy (HYP) is an established and preferred intervention for refractory symptoms in functional gastrointestinal disorders (FGIDs) and could be applied to FH. The objective of this study was to determine the feasibility, acceptability, and clinical utility of 7 weekly sessions of esophageal-directed HYP (EHYP) on heartburn symptoms, quality of life, and EHv. Similar to other work in FGIDs and regardless of hypnotizability, there were consistent and significant changes in heartburn symptoms, visceral anxiety, and quality of life and a trend for improvement in catastrophizing. We would recommend EHYP in FH patients who are either non-responsive to medications or who would prefer a lifestyle intervention.
功能性烧心（FH）是一种良性但令人困扰的病症，其特征为在无胃酸反流或症状与反流无相关性的情况下出现上腹部疼痛、烧灼感。食管超敏反应及其心理对应物——食管过度警觉（EHv）促使症状产生。催眠疗法（HYP）是功能性胃肠病（FGIDs）难治性症状既定且首选的干预措施，可应用于FH。本研究的目的是确定每周7次食管定向催眠疗法（EHYP）对烧心症状、生活质量和EHv的可行性、可接受性及临床效用。与FGIDs的其他研究相似，无论催眠感受性如何，烧心症状、内脏焦虑和生活质量均出现持续且显著的变化，灾难化思维有改善趋势。对于药物治疗无反应或更倾向于生活方式干预的FH患者，我们推荐采用EHYP。
