Jones R
Roborough Surgery, Plymouth, UK.
Fam Pract. 1996 Aug;13(4):369-72. doi: 10.1093/fampra/13.4.369.
This study aims to examine the aetiology, clinical features and response to treatment of childhood vulvovaginitis in general practice.
A longitudinal survey of consecutive premenarchal patients presenting with vulvovaginitis and/or vaginal discharge in the course of normal consultations with a general practitioner was conducted in a semi-rural, group general practice with 11,000 patients in Plymouth, UK. Forty-two premenarchal girls with vaginal inflammation or discharge were surveyed, with main outcome measures being clinical evaluation, microbiological assessment of urine and vaginal swabs, and patients' and parents' assessments of resolution and relapse of symptoms.
Non-specific vulvovaginitis with mixed bacterial flora, associated with poor hygiene and atrophic vaginal mucosa, was the commonest cause; specific bacteria were found in 10 out of 42 cases, including six of Streptococcus pyogenes. No candida was isolated. Treatment with topical oestrogen cream was effective only with mixed infection, oral antibiotics were effective in both mixed and single organisms. No evidence of sexual abuse nor foreign body was found.
Childhood vulvovaginitis is not uncommon in general practice, is usually associated with mixed growth of faecal organisms, and is seldom due to serious causes such as sexual abuse or foreign body.
本研究旨在探讨全科医疗中儿童外阴炎阴道炎的病因、临床特征及治疗反应。
在英国普利茅斯一家拥有11000名患者的半乡村团体全科诊所,对在正常会诊过程中出现外阴炎阴道炎和/或阴道分泌物的连续初潮前患者进行纵向调查。对42名患有阴道炎症或分泌物的初潮前女孩进行了调查,主要观察指标为临床评估、尿液和阴道拭子的微生物学评估,以及患者和家长对症状缓解和复发的评估。
伴有混合菌群的非特异性外阴炎阴道炎,与卫生状况差和阴道黏膜萎缩相关,是最常见的病因;42例中有10例发现特定细菌,其中6例为化脓性链球菌。未分离出念珠菌。局部雌激素乳膏治疗仅对混合感染有效,口服抗生素对混合感染和单一病原体感染均有效。未发现性虐待和异物的证据。
儿童外阴炎阴道炎在全科医疗中并不少见,通常与粪便微生物的混合生长有关,很少由性虐待或异物等严重原因引起。