Ramacciato G, Balesh A M, Fornasari V
First General Surgery Department, University of Rome, La Sapienza School of Medicine, Italy.
Am J Surg. 1996 Oct;172(4):358-62. doi: 10.1016/S0002-9610(96)00199-7.
Significant hemorrhage during hepatic resections for malignancies can result in increased mortality due to liver failure or acute blood loss. Massive hemorrhage is often related to loss of control or injury to the hepatic veins or inferior vena cava. Prevention or reduction of intraoperative blood loss, through improved surgical techniques and increased operator experience, can significantly reduce postoperative morbidity and mortality. Although the use of continuous or intermittent clamping of the portal triad structures (Pringle maneuver) has reduced the incidence of bleeding during hepatic transections, the hepatic vein ligation step of liver resections continues to be a possible source of major blood loss. Because of its safety, rapidity, and ease of application, the EndoGIA 30V vascular stapler is presented as an efficient means for controlling and dividing the major hepatic veins. In skilled hands, this stapling device can contribute to a reduction in incidence and risk of major intraoperative bleeding during hepatectomy. The critical factor to ensuring postoperative morbidity reduction, however, is the surgeon's experience in major hepatic resection procedures.
恶性肿瘤肝切除术中的大出血可因肝衰竭或急性失血导致死亡率增加。大出血通常与肝静脉或下腔静脉控制不佳或损伤有关。通过改进手术技术和增加术者经验来预防或减少术中失血,可显著降低术后发病率和死亡率。尽管使用门静脉三联结构的连续或间断阻断(Pringle手法)降低了肝切除术中出血的发生率,但肝切除术中肝静脉结扎步骤仍是大出血的一个可能来源。由于其安全性、快速性和易于应用,EndoGIA 30V血管吻合器被视为控制和离断主要肝静脉的有效手段。在技术熟练的术者手中,这种吻合器械有助于降低肝切除术中大出血的发生率和风险。然而,确保降低术后发病率的关键因素是外科医生在主要肝切除手术方面的经验。