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[具有长效抗菌活性的外科整形材料]

[Surgical plastic materials with prolonged antibacterial activity].

作者信息

Shalimov A A, Furmanov Iu A, Sil'chenko V P, Sharovol'skaia L N, Shrubovich V A

出版信息

Polim Med. 1977;7(1):19-26.

PMID:887523
Abstract

Sulphonation and further treatment with geomycine of surgical plastic articles (arterial prostheses, surgical threads) allowed to receive materials with prolongated surface antibacterial activity. The results of experiments on 200 animals proved the modified threads and prostheses to protect the bacteriostatic effect in surgical wounds within 2 to 10 days' period. The healing of implants was uncomplicated. The high antibacterial activity of these materials (500-1000 bacteriostatic doses) stands the radiosterilization and normal keeping conditions.

摘要

对外科塑料制品(动脉假体、手术缝线)进行磺化处理并进一步用土霉素处理,可得到具有延长表面抗菌活性的材料。对200只动物进行的实验结果证明,经改良的缝线和假体在2至10天内可在手术伤口中保持抑菌效果。植入物的愈合过程顺利。这些材料的高抗菌活性(500 - 1000个抑菌剂量)能耐受辐射灭菌和正常保存条件。

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