Van Loosen J, Van Zanten G A, Howard C V, Verwoerd-Verhoef H L, Van Velzen D, Verwoerd C D
Department of Otorhinolaryngology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Rhinology. 1996 Jun;34(2):78-82.
Using a specially designed algorithm for the measurement of the surface area of shapes with highly irregular contours, growth curves were developed for post-natal septal growth in humans using post-mortem specimens of a study population of 30 cases, distributed over the age range from birth to 62 years. From the results a rapid growth phase for the total septum is evident immediately after birth, lasting until the second year of life. Then, a gradual deceleration of growth is recognized with a plateau eventually being reached at the age of 36 years. Mathematical analysis of the growth curve shows that the curve for the total septum is the sum of two separate mathematical equations, representing the cartilaginous and bony contribution, respectively. It is demonstrated that the cartilaginous septum reaches adult dimensions (lateral surface area) at the age of two years. Subsequent growth of the septum is due to expansion of the perpendicular plate, i.e. the bony parts of the septum.
利用一种专门设计的算法来测量轮廓高度不规则的形状的表面积，通过对30例研究人群的尸检标本进行分析，这些标本年龄分布在从出生到62岁之间，从而得出了人类出生后鼻中隔生长的生长曲线。从结果可以看出，整个鼻中隔在出生后立即进入快速生长阶段，持续到生命的第二年。然后，生长逐渐减速，最终在36岁时达到平稳状态。对生长曲线的数学分析表明，整个鼻中隔的曲线是两个独立数学方程的总和，分别代表软骨和骨的贡献。结果表明，软骨性鼻中隔在两岁时达到成人尺寸（侧面表面积）。鼻中隔随后的生长是由于垂直板（即鼻中隔的骨性部分）的扩展。
