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一例与摄入硫化物有关的溺水病例——附动物实验报告

A case of drowning linked to ingested sulfides--a report with animal experiments.

作者信息

Imamura T, Kage S, Kudo K, Jitsufuchi N, Nagata T

机构信息

Department of Forensic Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

出版信息

Int J Legal Med. 1996;109(1):42-4. doi: 10.1007/BF01369601.

DOI:10.1007/BF01369601
PMID:8876322
Abstract

An adult male was found dead beneath a pool of sewage in the pump room of a fish market. Autopsy revealed the cause of death to be suffocation after aspirating sewage into the respiratory tract. Since hydrogen sulfide gas was detected in the atmosphere at the scene of the accident, gas poisoning was suspected and toxicological analysis of sulfides in body tissues was performed. The concentrations of sulfides in the blood, lung and kidney were 0.95 mumol@ml, 0.22 and 0.38 mumol/g, respectively. These values were remarkably higher than those in previously reported cases involving exposure to hydrogen sulfide gas. Therefore, oral intake of sulfides was assumed and the distribution of sulfides in tissues following oral administration of sodium sulfide solution was examined by means of animal experiments using rats. The concentration of sulfides in the blood from rats following oral intake was much higher than that seen following gas exposure. Based on these results, we concluded that the victim had been exposed to hydrogen sulfide gas and had then collapse into a pool of sewage containing sulfides. The sulfides which were distributed throughout the body tissues had mainly issued from the alimentary tract prior to death by drowning.

摘要

一名成年男性被发现死在鱼市泵房的一滩污水之下。尸检显示死因是呼吸道吸入污水后窒息。由于在事故现场的空气中检测到硫化氢气体,怀疑是气体中毒,并对身体组织中的硫化物进行了毒理学分析。血液、肺和肾中的硫化物浓度分别为0.95微摩尔/毫升、0.22和0.38微摩尔/克。这些值明显高于先前报道的涉及接触硫化氢气体的病例中的值。因此,假定有口服硫化物的情况,并通过对大鼠进行动物实验来研究口服硫化钠溶液后硫化物在组织中的分布。口服摄入后大鼠血液中的硫化物浓度远高于气体暴露后的浓度。基于这些结果,我们得出结论,受害者接触了硫化氢气体,然后跌入含有硫化物的污水池中。遍布全身组织的硫化物主要在溺水死亡前从消化道进入。

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